Mozilla Thunderbird
Mozilla
Flexible filtering system.
Not as user-friendly as other clients.
No longer in development.

Download Mozilla Thunderbird from its web page.Mozilla
Mozilla Thunderbird is a full-featured, secure, and functional email client.
It lets you handle mail efficiently with smart folders and various add-ons and filters away junk mail.
Spark
Readdle
Clean, modern design.

Spark Email client splash page.Readdle
Quick Replies function for short, templated responses.
Supports multiple email accounts.
Doesn’t support many services.

Spark’s scheduling feature allows you to assign a period during which it will send a particular message.
Select from times later today, in the evening, tomorrow, or any date.
Apple Mail
Included in the Mac operating system.

Supports smart folders and robust filters.
Markup tools for annotating photos or PDF attachments.
Basic design with limited customization features.

No option to snooze emails.
The Apple Mail system that ships with macOS is an easy-to-use email client optimized for Macs.
Mozilla SeaMonkey
All-in-one internet suite that includes email.
Some features aren’t intuitive.
No mobile rig support.
You may be interested in SeaMonkey if you’re an advanced user or a Mozilla fan.
It delivers HTML5, hardware acceleration, and improved JavaScript speed.
Mailspring
Integrates with Gmail, iCloud, Microsoft 365, and others.
Customizable with different layouts.
Some features limited to paid subscription.
Doesn’t support Exchange accounts.