Instructions cover Mail in macOS Catalina through OS X Lion.

Click theSignaturestab at the top of the MailPreferencesscreen.

SelectAll Signaturesor choose the account with a signature you want to edit in the left column of the screen.

Mail menu with Preferences selected

Select thesignaturefrom the middle column.

In the right panel, highlight the text to which you want to add a link in your signature.

SelectEdit>Add Linkfrom the menu bar, or use the keyboard shortcutCommand+K.

Mail Preferences with the Signatures tab highlighted

Enter the complete internet address for the link,including http://in the field provided, and clickOK.

Drag the signature fromAll Signaturesto the account you plan to use it with.

Selection of a signature in the Mail preferences

Signatures screen in macOS Mail preferences

Company name highlighted for macOS Mail signature link

Option to all Link to text in a macOS Mail signature

Signature preferences in macOS Mail

Email showing a text link in an email